Within what time frame do ACEI induced coughs typically begin after starting the medication?

ACE inhibitor (ACEI) induced coughs typically begin within a time frame of around 1 to 2 weeks after initiating treatment. This delay allows for the gradual accumulation of bradykinin, a peptide that can cause cough when ACE inhibitors block its breakdown. Although individual responses may vary, it is well-documented that the cough associated with ACE inhibitors often appears early in the treatment course, most commonly within the first two weeks.

Choosing two weeks as the correct timeframe aligns with clinical observations and studies that show a significant portion of patients start to experience this side effect shortly after starting therapy. While cough can occur at later times, its typical onset occurs earlier, making two weeks the most representative answer in practice.