What is the half-life of levothyroxine?

The half-life of levothyroxine is approximately 7 days, which is significant for understanding the drug's dosing and duration of action in the body. This relatively long half-life allows for once-daily dosing in most patients, which can enhance adherence to the medication regimen. It is crucial for healthcare providers to consider this half-life when monitoring thyroid hormone levels and adjusting dosages, as it influences how long it takes for the body to reach a steady state of the medication. Additionally, a longer half-life means that fluctuations in levothyroxine levels are minimized, providing a more stable therapeutic effect.