What does Peptic Ulcer Disease refer to?

Peptic Ulcer Disease specifically refers to the presence of ulcers in the lining of the stomach or the duodenum, which is the first part of the small intestine directly following the stomach. These ulcers occur as a result of the erosion of the mucosal lining due to the action of stomach acid and digestive enzymes. The primary causes of peptic ulcer disease are typically an infection with Helicobacter pylori bacteria and the long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).

While inflammation of the stomach lining can occur in relation to peptic ulcers, the term peptic ulcer disease itself denotes the specific formation of ulcers, making the correct choice focused on the presence of these ulcers in the stomach or duodenum.