What are the antibiotics of choice for MRSA?

The choice of antibiotics for treating Methicillin-resistant Staphylococcus aureus (MRSA) includes Bactrim (sulfamethoxazole/trimethoprim), clindamycin, and doxycycline due to their effectiveness against this resistant strain of bacteria.

Bactrim works by inhibiting bacterial folic acid synthesis, making it a suitable option for skin and soft tissue infections caused by MRSA. Clindamycin is effective because it targets bacterial protein synthesis and is particularly useful in cases of severe skin infections or those associated with toxic shock syndrome. Doxycycline is a tetracycline antibiotic that is often used for MRSA because of its ability to penetrate tissues and reach high concentrations within them, which is advantageous in treating infections located in the skin or deeper tissues.

These agents demonstrate adequate clinical efficacy and are often preferred, particularly in outpatient settings or when treating uncomplicated MRSA infections. Thus, the combination of these specific antibiotics aligns well with current guidelines and best practices for treating infections caused by MRSA.